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Inactivation of the von Hippel-Lindau tumour suppressor gene induces Neuromedin U expression in renal cancer cells

BACKGROUND: 209 000 new cases of renal carcinoma are diagnosed each year worldwide and new therapeutic targets are urgently required. The great majority of clear cell renal cancer involves inactivation of VHL, which acts as a gatekeeper tumour suppressor gene in renal epithelial cells. However how V...

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Detalhes bibliográficos
Principais autores: Harten, Sarah K, Esteban, Miguel A, Shukla, Deepa, Ashcroft, Margaret, Maxwell, Patrick H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155908/
https://ncbi.nlm.nih.gov/pubmed/21791076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-89
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