Mutation of von Hippel–Lindau Tumour Suppressor and Human Cardiopulmonary Physiology

BACKGROUND: The von Hippel–Lindau tumour suppressor protein–hypoxia-inducible factor (VHL–HIF) pathway has attracted widespread medical interest as a transcriptional system controlling cellular responses to hypoxia, yet insights into its role in systemic human physiology remain limited. Chuvash poly...

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Autori principali: Smith, Thomas G, Brooks, Jerome T, Balanos, George M, Lappin, Terence R, Layton, D. Mark, Leedham, Dawn L, Liu, Chun, Maxwell, Patrick H, McMullin, Mary F, McNamara, Christopher J, Percy, Melanie J, Pugh, Christopher W, Ratcliffe, Peter J, Talbot, Nick P, Treacy, Marilyn, Robbins, Peter A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479389/
https://ncbi.nlm.nih.gov/pubmed/16768548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030290
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