Mutation of von Hippel–Lindau Tumour Suppressor and Human Cardiopulmonary Physiology

BACKGROUND: The von Hippel–Lindau tumour suppressor protein–hypoxia-inducible factor (VHL–HIF) pathway has attracted widespread medical interest as a transcriptional system controlling cellular responses to hypoxia, yet insights into its role in systemic human physiology remain limited. Chuvash poly...

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Autors principals: Smith, Thomas G, Brooks, Jerome T, Balanos, George M, Lappin, Terence R, Layton, D. Mark, Leedham, Dawn L, Liu, Chun, Maxwell, Patrick H, McMullin, Mary F, McNamara, Christopher J, Percy, Melanie J, Pugh, Christopher W, Ratcliffe, Peter J, Talbot, Nick P, Treacy, Marilyn, Robbins, Peter A
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479389/
https://ncbi.nlm.nih.gov/pubmed/16768548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030290
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