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Biochemical properties and in vivo effects of the SOD1 zinc binding site mutant (H80G)
This work presents the initial characterization of transgenic mice with mutations in a primary zinc binding residue (H80), either alone or with a G93A mutation. H80G;G93A SOD1 transgenic mice developed paralysis with motor neuron loss, and ubquitin inclusion-type rather than mitochondrial vacuolar p...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155629/ https://ncbi.nlm.nih.gov/pubmed/21692800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07360.x |
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