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Transcriptional Profiling of Human Liver Identifies Sex-Biased Genes Associated with Polygenic Dyslipidemia and Coronary Artery Disease

Sex-differences in human liver gene expression were characterized on a genome-wide scale using a large liver sample collection, allowing for detection of small expression differences with high statistical power. 1,249 sex-biased genes were identified, 70% showing higher expression in females. Chromo...

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Autors principals: Zhang, Yijing, Klein, Kathrin, Sugathan, Aarathi, Nassery, Najlla, Dombkowski, Alan, Zanger, Ulrich M., Waxman, David J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155567/
https://ncbi.nlm.nih.gov/pubmed/21858147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023506
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