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The Relationship of Arginine Deprivation, Argininosuccinate Synthetase and Cell Death in Melanoma

It has been shown that melanoma cells do not express argininosuccinate synthetase (ASS) and therefore are unable to synthesize arginine from citrulline. Depleting arginine using pegylated arginine deiminase (ADI-PEG20) results in cell death in melanoma but not normal cells. This concept was translat...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Savaraj, Niramol, Wu, Chunjing, Kuo, Marcus Tien, You, Min, Wangpaichitr, Medhi, Robles, Carlos, Spector, Seth, Feun, Lynn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Libertas Academica 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155228/
https://ncbi.nlm.nih.gov/pubmed/21901069
Tagiau: Ychwanegu Tag
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