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Assessing directed evolution methods for the generation of biosynthetic enzymes with potential in drug biosynthesis
To address the synthesis of increasingly structurally diverse small-molecule drugs, methods for the generation of efficient and selective biological catalysts are becoming increasingly important. ‘Directed evolution’ is an umbrella term referring to a variety of methods for improving or altering the...
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Main Authors: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
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2011
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155183/ https://ncbi.nlm.nih.gov/pubmed/21644826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.48 |
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