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Computational design of a β–peptide that targets transmembrane helices
The design of β-peptide foldamers targeting the transmembrane (TM) domains of complex natural membrane proteins has been a formidable challenge. A series of β-peptides was designed to stably insert in TM orientations in phospholipid bilayers. Their secondary structures and orientation in the phospho...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155016/ https://ncbi.nlm.nih.gov/pubmed/21780757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja204215f |
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