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Infrared Signature and Folding Dynamics of a Helical β-Peptide

Synthetic foldamers consisting of β-amino acids offer excellent model systems for examining the effect of backbone flexibility on the dynamics of protein folding. Herein, we study the folding-unfolding kinetics of a β-peptide that folds into a 14-helical structure in water. We find that the T-jump i...

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Main Authors: Montalvo, Geronda, Waegele, Matthias M., Shandler, Scott, Gai, Feng, DeGrado, William F.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862463/
https://ncbi.nlm.nih.gov/pubmed/20373737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja100459a
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