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Reconstitution of lysosomal NAADP-TRP-ML1 signaling pathway and its function in TRP-ML1(−/−) cells
It is well known that the mutation of TRP-ML1 (transient receptor potential-mucolipin-1) causes mucolipidosis IV, a lysosomal storage disease. Given that lysosomal nicotinic acid adenine dinucleotide phosphate (NAADP)-Ca(2+) release channel activity is associated with TRP-ML1, the present study was...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154564/ https://ncbi.nlm.nih.gov/pubmed/21613607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00393.2010 |
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