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Ischemia-induced stimulation of Na-K-Cl cotransport in cerebral microvascular endothelial cells involves AMP kinase

Increased blood-brain barrier (BBB) Na-K-Cl cotransporter activity appears to contribute to cerebral edema formation during ischemic stroke. We have shown previously that inhibition of BBB Na-K-Cl cotransporter activity reduces edema and infarct in the rat middle cerebral artery occlusion (MCAO) mod...

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Bibliografiske detaljer
Main Authors: Wallace, Breanna K., Foroutan, Shahin, O'Donnell, Martha E.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154550/
https://ncbi.nlm.nih.gov/pubmed/21562306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00517.2010
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