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Altered contribution of RhoA/Rho kinase signaling in contractile activity of myometrium in leptin receptor-deficient mice

In late gestation, enhanced myometrial contractility is mediated in part through increased Rho/Rho kinase. Since leptin, which is elevated in pregnancy and obesity, can directly depress myometrial function, we hypothesized that in leptin receptor-deficient mice, myometrial contractility would be gre...

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Bibliografiske detaljer
Main Authors: Harrod, Jeremy S., Rada, Cara C., Pierce, Stephanie L., England, Sarah K., Lamping, Kathryn G.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154528/
https://ncbi.nlm.nih.gov/pubmed/21558549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00696.2010
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