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Designing of Highly Effective Complementary and Mismatch siRNAs for Silencing a Gene

In past, numerous methods have been developed for predicting efficacy of short interfering RNA (siRNA). However these methods have been developed for predicting efficacy of fully complementary siRNA against a gene. Best of author's knowledge no method has been developed for predicting efficacy...

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Détails bibliographiques
Auteurs principaux: Ahmed, Firoz, Raghava, Gajendra P. S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154470/
https://ncbi.nlm.nih.gov/pubmed/21853133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023443
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