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The Effect of Temperature on Gene Silencing by siRNAs: Implications for Silencing in the Anterior Chamber of the Eye
Gene silencing by siRNAs offers the potential for reducing the expression of mutated genes that cause disease. It has been shown that the folding or secondary structure of a specific mRNA was significantly correlated to the silencing observed. Since this base pairing is dependent on free energy, the...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1489385/ https://ncbi.nlm.nih.gov/pubmed/16466716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2005.12.003 |
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