A Novel α5GABA(A)R-Positive Allosteric Modulator Reverses Hyperactivation of the Dopamine System in the MAM Model of Schizophrenia

We have shown previously that aberrant hippocampal (HPC) output underlies the dopamine (DA) dysfunction observed in the methylazoxymethanol acetate (MAM) developmental model of schizophrenia in the rodent. This alteration of HPC activity was proposed to result from a reduction in parvalbumin (PV)-ex...

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書誌詳細
主要な著者: Gill, Kathryn M, Lodge, Daniel J, Cook, James M, Aras, Shamim, Grace, Anthony A
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2011
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154109/
https://ncbi.nlm.nih.gov/pubmed/21562483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.76
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