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S37. STATE-DEPENDENT EFFECTS OF D2 PARTIAL AGONIST ARIPIPRAZOLE ON DOPAMINE NEURON ACTIVITY IN THE MAM NEURODEVELOPMENTAL MODEL OF SCHIZOPHRENIA

BACKGROUND: Aripiprazole is an antipsychotic drug characterized by partial agonist activity at D2 receptors that impacts both hyperdopaminergic and hypodopaminergic states. It is unclear whether aripiprazole reduces dopamine neuron activity via inhibition or by excitation-induced depolarization bloc...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Sonnenschein, Susan, Gill, Kathryn, Grace, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888288/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby018.824
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