The Involvement of Cdk5 Activator p35 in Social Isolation-Triggered Onset of Early Alzheimer's Disease-Related Cognitive Deficit in the Transgenic Mice

Epidemiological studies indicate that isolated persons have increased risk of developing Alzheimer's disease (AD). This study investigated the cellular mechanisms of how social isolation influenced amyloid β peptide (Aβ) accumulation and affected the severity of AD-associated cognitive decline...

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Detalhes bibliográficos
Main Authors: Hsiao, Ya-Hsin, Chen, Po See, Chen, Shun-Hua, Gean, Po-Wu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154103/
https://ncbi.nlm.nih.gov/pubmed/21544067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.69
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