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Inhibition of eukaryotic translation elongation by the antitumor natural product Mycalamide B
Mycalamide B (MycB) is a marine sponge-derived natural product with potent antitumor activity. Although it has been shown to inhibit protein synthesis, the molecular mechanism of action by MycB remains incompletely understood. We verified the inhibition of translation elongation by in vitro HCV IRES...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3153980/ https://ncbi.nlm.nih.gov/pubmed/21693620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2624511 |
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