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Inhibition of Eukaryotic Translation Elongation by Cycloheximide and Lactimidomycin
Although the protein synthesis inhibitor cycloheximide (CHX) has been known for decades, its precise mechanism of action remains incompletely understood. The glutarimide portion of CHX is seen in a family of structurally related natural products including migrastatin, isomigrastatin and lactimidomyc...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831214/ https://ncbi.nlm.nih.gov/pubmed/20118940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.304 |
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