Low dose dextromethorphan attenuates moderate experimental autoimmune encephalomyelitis by inhibiting NOX2 and reducing peripheral immune cells infiltration in the spinal cord

Dextromethorphan (DM) is a dextrorotary morphinan and a widely used component of cough medicine. Relatively high doses of DM in combination with quinidine are used for the treatment of mood disorders for patients with multiple sclerosis (MS). However, at lower doses, morphinans exert anti-inflammato...

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Detaylı Bibliyografya
Asıl Yazarlar: Chechneva, Olga V., Mayrhofer, Florian, Daugherty, Daniel J., Pleasure, David E., Hong, Jau-Shyong, Deng, Wenbin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153572/
https://ncbi.nlm.nih.gov/pubmed/21704706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.06.004
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