Changes in Conformation at the Cytoplasmic Ends of the Fifth and Sixth Transmembrane Helices of a Yeast G Protein-Coupled Receptor in Response to Ligand Binding

The third intracellular loop (IL3) of G protein-coupled receptors (GPCRs) is an important contact domain between GPCRs and their G proteins. Previously, the IL3 of Ste2p, a Saccharomyces cerevisiae GPCR, was suggested to undergo a conformational change upon activation as detected by differential pro...

Full description

Saved in:
Bibliographic Details
Main Authors: Umanah, George K. E., Huang, Li-Yin, Maccarone, Julianna M., Naider, Fred, Becker, Jeffrey M.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153567/
https://ncbi.nlm.nih.gov/pubmed/21728340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200254h
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items