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Identification of Specific Transmembrane Residues and Ligand-Induced Interface Changes Involved In Homo-Dimer Formation of A Yeast G Protein-Coupled Receptor

The S. cerevisiae α-factor pheromone receptor, Ste2p, has been studied as a model for G protein-coupled receptor (GPCR) structure and function. Dimerization has been demonstrated for many GPCRs, although the role(s) of dimerization in receptor function is disputed. Transmembrane domains one (TM1) an...

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Main Authors: Kim, Heejung, Lee, Byung-Kwon, Naider, Fred, Becker, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783235/
https://ncbi.nlm.nih.gov/pubmed/19839649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901291c
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