A Role for Ethanol-Induced Oxidative Stress in Controlling Lineage Commitment of Mesenchymal Stromal Cells Through Inhibition of Wnt/β-Catenin Signaling

The mechanisms by which chronic ethanol intake induces bone loss remain unclear. In females, the skeletal response to ethanol varies depending on physiologic status (e.g., cycling, pregnancy, or lactation). Ethanol-induced oxidative stress appears to be a key event leading to skeletal toxicity. In t...

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Main Authors: Chen, Jin-Ran, Lazarenko, Oxana P, Shankar, Kartik, Blackburn, Michael L, Badger, Thomas M, Ronis, Martin J
Formato: Artigo
Idioma:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153370/
https://ncbi.nlm.nih.gov/pubmed/20200986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.7
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