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Inhibition of NADPH Oxidases Prevents Chronic Ethanol-Induced Bone Loss in Female Rats

Previous in vitro data suggest that ethanol (EtOH) activates NADPH oxidase (Nox) in osteoblasts leading to accumulation of reactive oxygen species (ROS). This might be a mechanism underlying inhibition of bone formation and increased bone resorption observed in vivo after EtOH exposure. In a rat mod...

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Detalhes bibliográficos
Main Authors: Chen, Jin-Ran, Lazarenko, Oxana P., Shankar, Kartik, Blackburn, Michael L., Lumpkin, Charles K., Badger, Thomas M., Ronis, Martin J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061541/
https://ncbi.nlm.nih.gov/pubmed/21098090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.175091
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