5-Lipoxygenase: Underappreciated Role of a Pro-Inflammatory Enzyme in Tumorigenesis

Leukotrienes constitute a group of bioactive lipids generated by the 5-lipoxygenase (5-LO) pathway. An increasing body of evidence supports an acute role for 5-LO products already during the earliest stages of pancreatic, prostate, and colorectal carcinogenesis. Several pieces of experimental data f...

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Detalhes bibliográficos
Main Authors: Steinhilber, Dieter, Fischer, Astrid Stefanie, Metzner, Julia, Steinbrink, Svenja Dorothea, Roos, Jessica, Ruthardt, Martin, Maier, Thorsten Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2010
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153017/
https://ncbi.nlm.nih.gov/pubmed/21833182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2010.00143
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