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Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair
Adeno-associated virus (AAV) mediates gene targeting in humans by providing exogenous DNA for allelic replacement through homologous recombination. In comparison to other methods of DNA delivery or alternative DNA substrates, AAV gene targeting is reported to be very efficient, perhaps due to its si...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152950/ https://ncbi.nlm.nih.gov/pubmed/20463753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.65 |
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