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A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice
We have discovered a distinct mature B-cell subset that accumulates with age, which we have termed age-associated B cells. These cells comprise up to 30% of mature B cells by 22 months. Despite sharing some features with other mature B-cell subsets, they are refractory to BCR and CD40 stimulation. I...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152496/ https://ncbi.nlm.nih.gov/pubmed/21562046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-330530 |
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