Extracellular signal-regulated kinase 1/2-mediated phosphorylation of p300 enhances myosin heavy chain I/β gene expression via acetylation of nuclear factor of activated T cells c1

The nuclear factor of activated T-cells (NFAT) c1 has been shown to be essential for Ca(2+)-dependent upregulation of myosin heavy chain (MyHC) I/β expression during skeletal muscle fiber type transformation. Here, we report activation of extracellular signal-regulated kinase (ERK) 1/2 in Ca(2+)-ion...

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Bibliographic Details
Main Authors: Meissner, Joachim D., Freund, Robert, Krone, Dorothee, Umeda, Patrick K., Chang, Kin-Chow, Gros, Gerolf, Scheibe, Renate J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Gene Regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152325/
https://ncbi.nlm.nih.gov/pubmed/21498542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr162
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