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Intracellular trafficking of perforin - to thwart a killer
How do killer cells restrain perforin, the most potent toxin known to biologists, at its point of synthesis in the endoplasmic reticulum, where conditions are ideal for its activation? In this Issue, Voskoboinik et al. study its trafficking, offering insights into protective mechanisms.
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151722/ https://ncbi.nlm.nih.gov/pubmed/21703535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.06.008 |
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