Actinomycin Analogues Containing Pipecolic Acid: Relationship of Structure to Biological Activity

Streptomyces antibioticus synthesizes a mixture of actinomycins which differ at the “imino acid” site of the peptide chains. In the presence of exogenous pipecolic acid, several new actinomycins were synthesized and 70% of the proline in the antibiotic mixture was replaced by the analogue. Three new...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Bacteriol
Päätekijät:	Formica, Joseph V., Shatkin, Aaron J., Katz, Edward
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 1968
Aiheet:	Microbial Physiology and Metabolism
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4174667/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.95.6.2139-2150.1968
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