Actinomycin Analogues Containing Pipecolic Acid: Relationship of Structure to Biological Activity

Streptomyces antibioticus synthesizes a mixture of actinomycins which differ at the “imino acid” site of the peptide chains. In the presence of exogenous pipecolic acid, several new actinomycins were synthesized and 70% of the proline in the antibiotic mixture was replaced by the analogue. Three new...

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Εκδόθηκε σε:	J Bacteriol
Κύριοι συγγραφείς:	Formica, Joseph V., Shatkin, Aaron J., Katz, Edward
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 1968
Θέματα:	Microbial Physiology and Metabolism
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4174667/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.95.6.2139-2150.1968
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