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Detection of autoreactive CD4 T cells using major histocompatibility complex class II dextramers
BACKGROUND: Tetramers are useful tools to enumerate the frequencies of antigen-specific T cells. However, unlike CD8 T cells, CD4 T cells - especially self-reactive cells - are challenging to detect with major histocompatibility complex (MHC) class II tetramers because of low frequencies and low aff...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151213/ https://ncbi.nlm.nih.gov/pubmed/21767394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-40 |
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