Direct Staining with Major Histocompatibility Complex Class II Dextramers Permits Detection of Antigen-Specific, Autoreactive CD4 T Cells In Situ

We report here the utility of major histocompatibility complex (MHC) class II dextramers for in situ detection of self-reactive CD4 T cells in two target organs, the brain and heart. We optimized the conditions for in situ detection of antigen-specific CD4 T cells using brain sections obtained from...

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Main Authors: Massilamany, Chandirasegaran, Gangaplara, Arunakumar, Jia, Ting, Elowsky, Christian, Kang, Guobin, Riethoven, Jean-Jack, Li, Qingsheng, Zhou, You, Reddy, Jay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903673/
https://ncbi.nlm.nih.gov/pubmed/24475302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087519
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