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TRIPTOLIDE AND TRAIL COMBINATION ENHANCES APOPTOSIS IN CHOLANGIOCARCINOMA
BACKGROUND: Cholangiocarcinoma originates from bile duct epithelial cells in the intrahepatic and extrahepatic biliary system. We recently observed that triptolide (a diterpenoid triepoxide) is effective in inducing apoptosis in pancreatic tumors. Death Receptors 4 and 5 are overexpressed in several...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151153/ https://ncbi.nlm.nih.gov/pubmed/20691980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2010.03.067 |
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