TRIPTOLIDE AND TRAIL COMBINATION ENHANCES APOPTOSIS IN CHOLANGIOCARCINOMA

BACKGROUND: Cholangiocarcinoma originates from bile duct epithelial cells in the intrahepatic and extrahepatic biliary system. We recently observed that triptolide (a diterpenoid triepoxide) is effective in inducing apoptosis in pancreatic tumors. Death Receptors 4 and 5 are overexpressed in several...

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Bibliographic Details
Main Authors: Clawson, K. A., Borja-Cacho, D., Antonoff, M. B., Saluja, A.K., Vickers, S. M.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151153/
https://ncbi.nlm.nih.gov/pubmed/20691980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2010.03.067
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