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Purification, crystallization and preliminary X-ray diffraction analysis of the human mismatch repair protein MutSβ

MutSβ is a eukaryotic mismatch repair protein that preferentially targets extrahelical unpaired nucleotides and shares partial functional redundancy with MutSα (MSH2–MSH6). Although mismatch recognition by MutSα has been shown to involve a conserved Phe-X-Glu motif, little is known about the lesion-...

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Bibliografske podrobnosti
Main Authors: Tseng, Quincy, Orans, Jillian, Hast, Michael A., Iyer, Ravi R., Changela, Anita, Modrich, Paul L., Beese, Lorena S.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151135/
https://ncbi.nlm.nih.gov/pubmed/21821902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111019300
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