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Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of a 12R-LOX–chaperone complex

Lipoxygenases are a family of nonheme iron-containing dioxygenases. An Escherichia coli expression system producing the bacterial chaperones GroES and GroEL was engineered and successfully used to produce large quantities of recombinant human 12R-LOX (LOXR; MW 80.34 kDa; 701 amino-acid residues). Th...

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Detalhes bibliográficos
Main Authors: Deb, Gouri, Boeshanes, Karen, Idler, William K., Ahvazi, Bijan
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151124/
https://ncbi.nlm.nih.gov/pubmed/21821891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111021361
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