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Vesicle-associated Membrane Protein-2 (VAMP2) Mediates cAMP-stimulated Renin Release in Mouse Juxtaglomerular Cells

Renin is essential for blood pressure control. Renin is stored in granules in juxtaglomerular (JG) cells, located in the pole of the renal afferent arterioles. The second messenger cAMP stimulates renin release. However, it is unclear whether fusion and exocytosis of renin-containing granules is inv...

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Detalhes bibliográficos
Main Authors: Mendez, Mariela, Gross, Kenneth W., Glenn, Sean T., Garvin, Jeffrey L., Carretero, Oscar A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151102/
https://ncbi.nlm.nih.gov/pubmed/21708949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225839
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