Asymmetric cancer cell division regulated by AKT

Human tumors often contain slowly proliferating cancer cells that resist treatment, but we do not know precisely how these cells arise. We show that rapidly proliferating cancer cells can divide asymmetrically to produce slowly proliferating “G0-like” progeny that are enriched following chemotherapy...

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Detalhes bibliográficos
Main Authors: Dey-Guha, Ipsita, Wolfer, Anita, Yeh, Albert C., G. Albeck, John, Darp, Revati, Leon, Eduardo, Wulfkuhle, Julia, Petricoin, Emanuel F., Wittner, Ben S., Ramaswamy, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150943/
https://ncbi.nlm.nih.gov/pubmed/21757645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109632108
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