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SPR-5 is a histone H3K4 demethylase with a role in meiotic double-strand break repair

Regulation of histone methylation levels has long been implicated in multiple cellular processes, many of which involve transcription. Here, however, we report a unique role for the Caenorhabditis elegans histone demethylase SPR-5 in meiotic DNA double-strand break repair (DSBR). SPR-5 shows enzymat...

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Detalhes bibliográficos
Main Authors: Nottke, Amanda C., Beese-Sims, Sara E., Pantalena, Luiz F., Reinke, Valerie, Shi, Yang, Colaiácovo, Monica P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150895/
https://ncbi.nlm.nih.gov/pubmed/21768382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102298108
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