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TNF and IL-10 are major factors in modulation of the phagocytic cell environment in lung and lymph node in tuberculosis: a next generation two compartmental model

Tuberculosis (TB) is one of the earliest recorded human diseases and still one of the deadliest worldwide. Its causative agent is the bacteria Mycobacterium tuberculosis (Mtb). Cytokine-mediated macrophage activation is a necessary step in control of bacterial growth, and early immunologic events in...

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Bibliographische Detailangaben
Hauptverfasser: Marino, Simeone, Myers, Amy, Flynn, JoAnne L., Kirschner, Denise E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150786/
https://ncbi.nlm.nih.gov/pubmed/20510249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2010.05.012
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