Differences in Reactivation of Tuberculosis Induced from Anti-TNF Treatments Are Based on Bioavailability in Granulomatous Tissue

The immune response to Mycobacterium tuberculosis (Mtb) infection is complex. Experimental evidence has revealed that tumor necrosis factor (TNF) plays a major role in host defense against Mtb in both active and latent phases of infection. TNF-neutralizing drugs used to treat inflammatory disorders...

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Detalhes bibliográficos
Main Authors: Marino, Simeone, Sud, Dhruv, Plessner, Hillarie, Lin, Philana Ling, Chan, John, Flynn, JoAnne L, Kirschner, Denise E
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041971/
https://ncbi.nlm.nih.gov/pubmed/17953477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030194
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