Propofol anaesthesia does not alter regional rates of cerebral protein synthesis measured with L-[1-(11)C]leucine and PET in healthy male subjects

We report regional rates of cerebral protein synthesis (rCPS) in ten healthy young males each studied under two conditions: awake and anaesthetized with propofol. We used the quantitative L-[1-(11)C]leucine PET method to measure rCPS. The method accounts for the fraction (λ) of unlabeled leucine in...

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Detalhes bibliográficos
Main Authors: Bishu, Shrinivas, Schmidt, Kathleen C, Burlin, Thomas, Channing, Michael, Horowitz, Lisa, Huang, Tianjiang, Liu, Zhong-hua, Qin, Mei, Vuong, B-K, Unterman, Aaron, Xia, Zengyan, Zametkin, Alan, Herscovitch, Peter, Quezado, Zenaide, Smith, Carolyn Beebe
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150740/
https://ncbi.nlm.nih.gov/pubmed/19223912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.7
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