Use of acute hyperphenylalaninemia in rhesus monkeys to examine sensitivity and stability of the l-[1-(11)C]leucine method for measurement of regional rates of cerebral protein synthesis with PET

We have previously shown by direct comparison with autoradiographic and biochemical measurements that the l-[1-(11)C]leucine positron emission tomography method provides accurate determinations of regional rates of cerebral protein synthesis (rCPS) and the fraction (λ) of unlabeled leucine in the pr...

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Autori principali: Smith, Carolyn B, Schmidt, Kathleen C, Bishu, Shrinivas, Channing, Michael A, Bacon, Jeff, Burlin, Thomas V, Qin, Mei, Liu, Zhong-hua, Xia, Zengyan, Huang, Tianjiang, Vuong, Bee-Kee, Herscovitch, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531290/
https://ncbi.nlm.nih.gov/pubmed/18431402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.27
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