FUS and TARDBP but Not SOD1 Interact in Genetic Models of Amyotrophic Lateral Sclerosis

Mutations in the SOD1 and TARDBP genes have been commonly identified in Amyotrophic Lateral Sclerosis (ALS). Recently, mutations in the Fused in sarcoma gene (FUS) were identified in familial (FALS) ALS cases and sporadic (SALS) patients. Similarly to TDP-43 (coded by TARDBP gene), FUS is an RNA bin...

Full description

Saved in:
Bibliographic Details
Main Authors: Kabashi, Edor, Bercier, Valérie, Lissouba, Alexandra, Liao, Meijiang, Brustein, Edna, Rouleau, Guy A., Drapeau, Pierre
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150442/
https://ncbi.nlm.nih.gov/pubmed/21829392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002214
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items