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FUS and TARDBP but Not SOD1 Interact in Genetic Models of Amyotrophic Lateral Sclerosis

Mutations in the SOD1 and TARDBP genes have been commonly identified in Amyotrophic Lateral Sclerosis (ALS). Recently, mutations in the Fused in sarcoma gene (FUS) were identified in familial (FALS) ALS cases and sporadic (SALS) patients. Similarly to TDP-43 (coded by TARDBP gene), FUS is an RNA bin...

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Detalhes bibliográficos
Main Authors: Kabashi, Edor, Bercier, Valérie, Lissouba, Alexandra, Liao, Meijiang, Brustein, Edna, Rouleau, Guy A., Drapeau, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150442/
https://ncbi.nlm.nih.gov/pubmed/21829392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002214
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