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Prevention of lymphocyte apoptosis in septic mice with cancer increases mortality

Lymphocyte apoptosis is thought to play a major role in the pathophysiology of sepsis. However, there is a disconnect between animal models of sepsis and patients with the disease, since the former use subjects that were healthy prior to the onset of infection while most patients have underlying com...

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Autores principales: Fox, Amy C., Breed, Elise R, Liang, Zhe, Clark, Andrew T., Zee-Cheng, Brendan R., Chang, Katherine C., Dominguez, Jessica A., Jung, Enjae, Dunne, W. Michael, Burd, Eileen M., Farris, Alton B., Linehan, David C., Coopersmith, Craig M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150286/
https://ncbi.nlm.nih.gov/pubmed/21734077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003391
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