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Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources

We present a method of targeted DNA sequence retrieval from DNA sources which are heavily degraded and contaminated with microbial DNA, as is typical of ancient bones. The method greatly reduces sample destruction and sequencing demands relative to direct PCR or shotgun sequencing approaches. We use...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Briggs, Adrian W., Good, Jeffrey M., Green, Richard E., Krause, Johannes, Maricic, Tomislav, Stenzel, Udo, Pääbo, Svante
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MyJove Corporation 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150061/
https://ncbi.nlm.nih.gov/pubmed/19730410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/1573
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