Timing of human protein evolution as revealed by massively parallel capture of Neandertal nuclear DNA sequences

Whole genome shotgun sequencing is now possible for extinct organisms, as well as the targeted capture of specific regions. However, targeted resequencing of megabase sized parts of nuclear genomes has yet to be demonstrated for ancient DNA. Here we show that hybridization capture on microarrays can...

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Main Authors: Burbano, Hernán A., Hodges, Emily, Green, Richard E., Briggs, Adrian W., Krause, Johannes, Meyer, Matthias, Good, Jeffrey M., Maricic, Tomislav, Johnson, Philipp L.F., Xuan, Zhenyu, Rooks, Michelle, Bhattacharjee, Arindam, Brizuela, Leonardo, Albert, Frank W., de la Rasilla, Marco, Fortea, Javier, Rosas, Antonio, Lachmann, Michael, Hannon, Gregory J., Pääbo, Svante
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140021/
https://ncbi.nlm.nih.gov/pubmed/20448179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1188046
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