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Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

The three-dimensional folding of chromosomes compartmentalizes the genome and and can bring distant functional elements, such as promoters and enhancers, into close spatial proximity (2-6). Deciphering the relationship between chromosome organization and genome activity will aid in understanding gen...

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Detalhes bibliográficos
Main Authors: van Berkum, Nynke L., Lieberman-Aiden, Erez, Williams, Louise, Imakaev, Maxim, Gnirke, Andreas, Mirny, Leonid A., Dekker, Job, Lander, Eric S.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149993/
https://ncbi.nlm.nih.gov/pubmed/20461051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/1869
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