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Response to Combined Molecular Targeting: Defining the Role of P-STAT3
Src family kinase- (SFK-) targeting agents are currently undergoing clinical investigation for treatment of solid malignancies. EGFR-independent phosphorylation of STAT3 (P-STAT3) has been identified as a mechanism of tumor resistance to agents targeting SFK. Tumor P-STAT3 levels may be an important...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149866/ https://ncbi.nlm.nih.gov/pubmed/21266530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2925 |
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