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Using the water signal to detect invisible exchanging protons in the catalytic triad of a serine protease

Chemical Exchange Saturation Transfer (CEST) is an MRI approach that can indirectly detect exchange broadened protons that are invisible in traditional NMR spectra. We modified the CEST pulse sequence for use on high-resolution spectrometers and developed a quantitative approach for measuring exchan...

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Detalhes bibliográficos
Main Authors: Lauzon, Carolyn B., van Zijl, Peter, Stivers, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149851/
https://ncbi.nlm.nih.gov/pubmed/21809183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-011-9527-z
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