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Using the water signal to detect invisible exchanging protons in the catalytic triad of a serine protease
Chemical Exchange Saturation Transfer (CEST) is an MRI approach that can indirectly detect exchange broadened protons that are invisible in traditional NMR spectra. We modified the CEST pulse sequence for use on high-resolution spectrometers and developed a quantitative approach for measuring exchan...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149851/ https://ncbi.nlm.nih.gov/pubmed/21809183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-011-9527-z |
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